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Saturday 12 June 2010

It Started with a Canine-Adult Stem Cell and Cloning

It Started with a Canine-Adult Stem Cell and Cloning

The use of adult stem cells to cure sickness among out canine companions is common nowadays. Veterinarian clinics have been performing stem cell renewal to address dogs ailing due to old age, arthritis, or broken bones.

Several mammals, like cows, sheep, mice, horse, mule, rabbits, have been cloned using almost the same process similar to adult stem cell. Clone means that two organisms have the same DNA construct or the same genome. Blastocysts are obtained, they are also called pre-embryo and is mass of undifferentiated cells.

Each of the obtained blastocysts has the potential to generate an individual, but that is not a goal. The goal is to use these undifferentiated cells, also called embryonic stem cells, to generate any time of issue. This stock of stem cells can then be used to treat diseases. You can call this therapeutic cloning.

Much research is being done in developing therapeutic cloning. When developed it can be used against life-threatening disease such as AIDS, Parkinson’s disease, Alzheimer’s disease, diabetes and other sicknesses. How could it work? Alzheimer’s disease results into dying neurons, it is possible to use cells to treat the degenerative disease.

The use of stem cells, whether it is embryonic and adult, is to regenerate or replace diseased tissue, like in Parkinson’s disease or multiple sclerosis. An advantage of a adult stem cells, is that the patient’s own stem cells can be used on his own body. This removes the risk of rejection, or the immune reactions against reimplanting these cells. In the embryonic stel cemm, exogenous cells are used. They may provoke an immune reaction or response. That is where the therapeutic cloning comes in.

A nucleus is extracted from the body cell, it is then inserted into a denucleated egg cell and the embryonic development is stimulated. It gets cultured and will eventually transfor into the needed tissue which will be transplanted again to the patient for treatment.

But recent medicine has not yet reached this height. There are still no report for successful treatments in kind of human cases using this way. Embryonic stem cell have high tumor risk. But researches are still in the dawn of discovering something or technique that will pave a way for medical change.

But is it really as good as this?

There are some researchers who argue that the adult stem cells are not as it regenerative as it claims. A scientific panel cited a 2002 study showing that adult stem cells are useful as embryonic ones are flawed may be wrong.

They make three common claims about adult stem cells: They already work as therapies, while embryonic stem cells are still experimental; they are derived without killing embryos; and — last but not least — they are safe compared to embryonic stem cells, which are known to cause tumors.

Stem cells have been the subject of much controversy in recent years. Supporters of stem cell research promise successful therapies in the future. Opponents are concerned about the ethics of using embryonic stem cells for research - such stem cells inherently require the destruction of human embryos.

Adult stem cells - which do not involve embryo destruction - are another option for research, and have great potential for successful therapies in the future. It ma have started or popularly used in canine bodies, but there is a future for humans receiving the same treatments for dogs.


John Caldecott.

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