Dogsballs

Saturday, 12 June 2010

Harnessing Adult Canine Stem Cells For Healing

Harnessing the ability of canine adult stem cells for healing body damage is by far an innovative breakthrough in medical science for the treatment of every possible illness of man’s best friend

Like humans, when a dog breaks a bone or tears a ligament, the body’s natural response is to repair itself as a healing process and the cells that are responsible for this is called the stem cells.

Recent studies have identified that the canine adult stem cell has been regarded as one of the most prominent stem cell type that can be used for regenerative and reparative properties for the four legged species.

Canine adult stem cells are basically undifferentiated cells that can be found throughout the dog’s body that divide and replenish dying cells, as well as repair damaged tissues and bones.

The primary role of a canine adult stem cell in the dog’s body is to maintain, as well as repair damaged tissues in the body.

Ideally the main focus of canine adult stem cell research was for health and therapeutic concerns, especially with the stem cell’s regenerative and reparative properties, as a precursor to research done on human adult stem cells.

Research on canine adult stem cells is a continued intensive process that determines how an organism develops from a single cell and how healthy stem cells replace damaged cells in adult living organisms.

The canine adult stem cell also play key roles in replacing muscle, bone or blood cells, especially in healthy adult dogs, even with the normal wear and tear of cells and tissues.

Currently, studies have established that canine adult stem cells have been found in many organs and tissues, however, there were recent discoveries that there are a small number of stem cells in each muscle or bone tissue.

These canine adult stem cells are believed to be embedded in a specific area of a tissue, where each stem cell may remain inactive for years at a time and will only be activated for regeneration once that particular tissue is damaged by disease or injury.

Adult tissues that have been found out to have reportedly been identified to contain these fascinating adult stem cells that include the bone marrow, blood vessels, skeletal muscle, liver and the brain.

Many scientific studies into the canine adult stem cell involve tests to find out ways and processes to culture adult stem cells and manipulate the stem cells to create specific cell types that will match tissues, which could prove helpful in the treatment of injury or disease, especially those that are commonly afflicting dogs like hip dysplasia and liver disease due to poor nutrition.

Current milestones into the studies and findings made on canine adult stem cells will continue to astound and create awe, since it has opened new doors for the scientific community, as well as setting new heights for the treatment of once-enigmatic diseases among dogs.

Hopefully with more intensive studies, canine adult stem cells will continue to provide more solutions to many other health problems, as well as shed light on the mystery that has afflicted man’s best friend.

Harnessing adult canine stem cells for healing many diseases that continue to afflict dogs will pave the way for providing hope to pet owners around the world.

John Caldecott.

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Canine 911

Canine adult stem cell rapidly improving and adapting to the times. Adult stem cells theraoies are used to treat disease today. The probably most well known stem cell therapy use is the umbilical cord blood stem cell transplants and the peripheral blood stem cells and bone marrow stem cell transplants.

Cell therapy make it possible to clone organs which can be transplanted into humans whose livers, kidneys, heart is failing. The most important potential application of human stem cells is the generation of cells and issues that could be used for cell-based therapies.

When your canine friend gets sick brought about by old age, like tear a ligament or tissue and skeleton fails to heal, adult stem cells are the body’s natural system of renewal. Fewer stem cells are released into circulation as the dog reaches a mature and older age. When there is a high number of circulating stem cells in the canine or human, the faster and more complete is the repair and renewal. More stem cells in circulation, better overall health. Who would want our canine friends to be dire health situations?

What are the common sicknesses that adult stem cell can cure?

Surprisingly, adult stem cell can cure stroke and traumatic bran injury. In healthy adult animals, progenitor cells migrate within the brain and function primarily to maintain neuron populations for olfaction (the sense of smell). In case of a brain injury, substantial recovery is rarely observed in adults, suggesting a lack of robustness.

Aside from brain injury, adult stem cells in the brains of the dogs has shown to be very successful in treating cancerous tumors. With traditional techniques, brain cancer is almost impossible to treat because it spreads rapidly. Stem cells neither differentiated nor turned tumorigenic cells. The current cancer treatments are designed to kill all cancer cells, but through this method, researches would be able to develop drugs to specifically target these stem cells.

Lymphomas and hematopoietic cancers to HIC, the disruption of cell homeostasis within the immune system commonly leads to disease. The specificity of one’s immune cell repertoire, which allows it to recognize foreign antigen, causes further challenges in the treatment of immune disease. Identical matches between donor and recipient must be made for successful transplantation treatments, while matches are uncommon, even between first-degree relatives. Research using both hematopoietic adult stem cells and embryonic stem cells has contributed great insight into possible mechanisms and methods of treatment for many of these ailments.

Baldness and missing teeth can also be addressed by adult stem cell treatment. Hair follicles also contain stem cells, and some researches predict research on these follicle stem cells. Baldness can be treated by hair multiplication which is also known as hair cloning. Researches are also confident that adult stem cell research can also be used to grow live teeth. Deafness, blindness and vision impairment can also be restored by adult stem cell treatment.

Stem cells are harvested from the dog’s fat. The stem cells harvested are injected into the dog’s painful body part. Stem cells have ability to differentiate tissues. Since the stem cells came from the pet they are injected to, it is almost impossible for rejection.

If ever the stem cell get rejected, an ovum will be harvested from an animal and its DNA will be sucked out. Then new DNA would be extracted from a cell in the patient and inserted into the evacuated ovum, creating the patient’s embryonic clone.

Is your dog a candidate for canine adult stem cell treatment? Dogs that have not responded or cannot tolerate non-steroidal anti-inflammatory drugs and dogs that are not good candidates for orthopedic surgery are some of the candidates for stem cell treatment. While dogs with early arthritis or have multiple joints afflicted with arthritis are also candidates for stem cell treatment.

John Caldecott.

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Adult Canine Stem Cell Research

Adult canine stem cell research, breaking the silence between ethics and medical breakthroughs

It is indeed a dilemma where the line is drawn on adult canine stem cell research, as it aims to break the silence between ethics and medical breaktroughs.

Arguments and debates have been raised about the propriety and the need to focus on stem cell ethics, now that adult canine stem cells are already being introduced as a treatment procedure for some diseases and illnesses among dogs.

Regardless of the idea that stem cell research is primarily aimed at tapping into the potential benefits of adult canine stem cells on areas of health and medical treatment for dogs, a black cloud still looms over the eventual effects of the process ranging from birth defects to cancer.

The scientific community has recently been hounded by calls for protests and objections to continued research and experimentation, particularly with the embryonic stem cells, which are being isolated from days-old embryos of a variety of living organisms, be it human or animal.

Some of the stem cell lines, which have also raised some eyebrows, are those that have also been developed from animal tissue, apparently on the stage where the living organism is into its eighth week of development or even later.

Recent protests are lobbying for a holistic approach to advancements in science and technology, particularly on maintaining a balance between the technological aspects and being aware of ethical principles in the pursuit of medical breakthroughs.

Advocates in favor of applied stem cell ethics insist that this check and balance process needs to be set-up, in order to maintain certain standards on the limitations of these tests and researches.

Only recently these calls have been heeded by the scientific community after it proposed to impose a series of ethical guidelines that will govern stem cell research and experiments.

The proposed stem cell ethics system, albeit voluntary, will serve as an institutional policy that will apply to all stem cell researches and experiments, whether funded privately or publicly, since it is expected to be governed by federal and state regulations.

Although stem cell research breakthroughs have been showing good progress, but since the process requires deriving the stem cells from embryos and eventually destroying them, multi-sectoral groups have denounced the process.

Stem cell ethics is one way to ensure the public that stem cell research is being conducted in consideration of every possible ethical principle governing life.

Although the scientific community established the ethical guidelines to assuage the public’s fears of a blanket authority over such experiments and studies, political groups opposed to adult canine stem cell research charge that these guidelines is only meant to euphemize a ’seemingly unethical line of research.’

Stem cell research has been one of the most recently celebrated controversies today, which has called for the imposition of a stem cell ethics framework and should consider all possible ethical viewpoints since human life is involved, even while it was still an ‘insignificant’ organism inside the body.

Regardless of whether the research is for human or adult canine stem cell research, pro-life advocates maintain the in general, all living organisms have the right to life and exist.

Truth be told, that even with the difference between human or adult canine stem cell research, breaking the silence between ethics and medical breakthroughs will continue to be a controversy of choice.

John Caldecott.

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A Look Into Adult Canine Stem Cell Research

A look into adult canine stem cell research, just like any other stem cell research, often raises controversy and draws the line between scientific breakthroughs and the raising of eyebrows among skeptics.

At the turn of the century, stem cell research, has become one of the most controversial and celebrated events in the history of the world.

From the research laboratories where tests and experimentations are conducted, down to the streets filled with protesters hoping to stop stem cell experiments or those pushing for ethical principles behind the experiments, stem cell research has by far been the most talked about topic in scientific history.

Although much has been said about many innovative breakthroughs in harnessing the power of stem cells, stem cell research still has a long way to go.

With breakthroughs achieved, allowing adult canine stem cells to be used in treatment of a variety of diseases among dogs, still further intensive studies are being conducted since many scientists believe that stem cell therapy holds the promise of radically changing the way canine diseases are being treated.

For example, adult canine stem cells are currently gaining widespread use for treatment and therapy, as well as not posing any medical danger to the patient, since findings have already been established about the regenerative and renewal properties of the adult canine stem cell without destructive or damaging side effects.

Adult canine stem cells, also called somatic stem cells, are found throughout the dog’s body and has been linked to the healing properties of living organisms like for example, the ability of the skin to regenerate after it has been injured or the ability of regenerating human tissues due to wear and tear.

Theoretically, with findings on recent stem cell research, scientists believe that it may lead the way to addressing better treatment and therapy of certain types of muscle damage, even cancer, as well as with varied forms of tissue or organ impairments and other medical conditions – both treatable and what may have been thought of as untreatable.

Regardless of the benefits of stem cell research and its medical breakthroughs, however, controversies are still rife since the process of obtaining a canine embryonic stem cell for experimentation.

Deriving an active embryonic stem cell line through therapeutic cloning would require destroying a canine embryo, since many oppositionists to stem cell research argue that this is a similar process to reproductive cloning and is no less an ethical question why the need to subject the life of a living organism to become an instrument of science.

Proponents, however, insist that the pursuit of medical breakthroughs and scientific experiments on the embryonic stem cell is only limited to embryonic samples that are already subject for destruction resulting from in vitro fertilization.

This argument, however, is also being countered by pro-life movers who insist that despite of the process, an embryo is still a living organism, thus has the right to life regardless of the fact that it is already subject for destruction.

The never-ending battle between good and evil is seemingly manifested in stem cell research, since it has created a contrasting atmosphere of animosity and excitement over findings resulting from these researches from various sectors, and will continue to face social and ethical challenges for all sectors concerned.

All the same, a look into adult canine stem cell research – regardless of the challenges it faces- will continue to provide answers and pave the way for more breakthroughs ahead.

John Caldecott.

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Monday, 7 June 2010

Be the Top Dog

Be the Top Dog

When you’re trying to train your dog, it’s important to understand how your
dog thinks.

Dogs are pack animals, first and foremost, and that’s something you need to understand to have the best possible relationship you can with your pet.

If you understand this basic concept, it’ll be easer to train your dog.

Dogs are happy to be around humans and make excellent companions
when puppies and adults.

They naturally take to people and families because their instinct
for packs makes it easy for them to find a place in a group.

Pack animals separate their pack into levels, with the leader of the pack at the top.

This leader sets the direction for the pack.

The next level is like the second in command, and each one down has less
dominance in the group until you reach the bottom.

When in a pack, dogs understand where each animal in the group sits on that pyramid, and they fall into those roles naturally.

Because it’s their instinct, dogs will also naturally want to be part of a pack, or group, and that’s what makes them fall so easily in a family group of people.

When you bring a puppy or even an adult dog home, it automatically views
everyone in the household as part of a pack.

And by instinct it needs to immediately determine where it falls into the family pack; it needs to understand what level it belongs in.

Your dog will need to understand who leads and who follows.

Problems arise when no one seems to be the clear leader.

If you don’t establish yourself as head of the pack right away, your dog will be uncomfortable that there is no leader.

And your dog’s instinct will be to become the leader, to ensure that the pack is strong.

Even a puppy will attempt to fill the leader role, because it knows that there must be one.

If you establish yourself as the leader right away, though, your dog will fall
into its spot on the pack pyramid and happily view you as the one in charge.

There are several important things you can do to make sure your dog knows
that you’re the boss.

• Physical contact.
It’s important that you pet and groom your dog.

Even if your pet doesn’t like being brushed or having his nails clipped,
don’t show that you’ll defer to his wishes.

• Ground rules.

Don’t let her chew on your shoes because you think it’s cute, unless you want her to chew on your shoes forever.

You’ll confuse her later for punishing her for doing the same thing.

• Be consistent.

If you don’t want your dog to something, stop him every
time and don’t ever let it go.

Be consistent with your praise, and do praise your dog when he does things right.

Following these basic rules to establish yourself as in charge will save you
a great deal of frustration as your puppy grows.

John Caldecott.

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Basic Puppy Training Techniques

Basic Puppy Training Techniques

There are a number of important guidelines that you need to keep in mind
when teaching your puppy the basics about good behavior.

Exercising the right training techniques is what will make or break your training regimen with your dog.

Follow these five important guidelines and teaching your puppy will be
easier than ever.

1 - Be Gentle - Your new puppy is going to be extremely sensitive at first,
and as a result will not be able to handle anything that is too stressful on both an emotional and a physical level.

Although learning generally quickly takes place, now is the time where your puppy will react poorly to stress or being trained too rough.

If fears are picked up too easily during the training process, then it may inhibit the puppy's ability to learn, so make sure to be gentle but firm in your training.

2 - Keep Things Brief - Puppies have even shorter attention spans than children.

Your puppy is only going to learn when his or her attention is on you, and you will not see the results that you are looking for when your puppy is tired physically or mentally.

Make sure to be brief when putting your puppy through training activities, and then you can move on.

3 - Exercise Patience - Expecting overnight results is only going to frustrate
you and cause your training regimen to lose its focus.

Relax, and understand that things like this will take time, and puppies learn in spurts.

Puppies also do go through brief memory lapses so do not allow yourself to become overwhelmed if your puppy seems to forget some of its training from one day to the next.

Exercise patience when it comes to training and you will be just fine.

4 - Exercise Simplicity - Teaching your puppy should be done in a step by
step process if you want to attain the best results.

This is the best way that your puppy will learn.

Exercise a simple, step by step approach and your puppy will learn more quickly and will enjoy the process more thoroughly than if you were to employ a more intensive training regimen.

5 - Build Confidence - Confidence is the core of every healthy adult dog, and
confidence begins with building confidence in a young puppy.

Building confidence in your puppy is not hard at all to do; all you need to do is spend positive time with your puppy as often as you possibly can.

This will help to build self confidence in your puppy.

You should not always be in training mode when you first get your puppy, but instead sometimes you should step back and play with your dog, having fun with him or her in the process.

Training is important, but above all else your dog needs to know that you are friends.

These five fundamental training foundations are vital in preparing your puppy
for an effective training regimen and will drive better results when properly
integrated into your step by step puppy training process.

John Caldecott.

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Some Interesting Facts about Dogs

Some very interesting puppy facts:

• When puppies are first born, they are blind, deaf, and have no teeth.
• 90% of a puppy’s time is spent sleeping during the first week of their lives;
the remaining 10% of time is spent eating.
• When a puppy reaches the age of 2 to 3 weeks it begins to get its vision.
• At the age of 3 weeks, puppies develop their sense of smell.
• Some dogs reach sexual maturity at the young age of eight months.
• When a puppy reaches the age of one year it is considered to be an adult.

Some other dog facts which you may find interesting include:

• A dog has forty-two teeth.
• America’s first canine movie star was Rin Tin Tin.
• Dogs have three eyelids: an upper and lower eyelid and also a third eyelid.

It is the third eyelid that helps to protect a dog’s eyes from dirt and dust.
It is referred to as the “haw”.

• Dogs see in color, though not with such a bright spectrum as humans.
• Female dogs tend to bite more than male dogs.
• It was always thought that Lassie, the canine television star, was a female;

However all male dogs were used when filming.

• Smaller dog breeds mature earlier than larger breeds.
• Smaller dog breeds tend to have a longer lifespan than larger breeds.
• The Basenji is the only non-barking dog in the world.
• The spots on a Dalmatian appear as they mature, they are not born with them.
• There are 321 bones in a dog’s body.
• There are 701 different dog breeds.

There are also many interesting dog facts when it comes to the anatomy.

These facts include:

• A dog’s heart beats between 70 and 120 times per minute.
• A dog’s temperature is between 100.2 and 102.8 degrees Fahrenheit.
• Dogs take between 10 and 30 breaths every minute.
• Dogs can hear sounds 250 yards away, whereby most humans cannot hear more than
25 yards away.
• Dogs sweat through the pads of their feet, not by salivating.
• The number of milk teeth that a young dog possesses is 28.

I hope that you found these dog facts interesting and you may be inclined to

pass some on to your friends - who knows, they may even help you win a quiz one

day!

You will be well aware that dogs are the most faithful companions man can

ever have.

However; not only are they man’s (and a Womans) best friend; they are also second to none in other areas, such as:

• They can lead the blind and assist the handicapped.
• They can assist law enforcement officials.
• They can even cheer the elderly in nursing homes.
• They are intelligent and loving animals.
• They have been known to rescue humans.
• They watch over their human families.

• The largest dog is the Irish Wolfhound;
• The tallest dog is the Great Dane;
• The heaviest dog is the St. Bernard;
• The smallest dog is the Chihuahua;
• The fastest dog is the Greyhound, which can reach a speed of 45 miles per hour;
• 29 years and 5 months was the age of the world’s oldest dog,
which was an Australian cattle-dog by the name of Bluey;

. One of the largest dogs recorded by the Guiness Book of World Records was Cloe, a mastiff who weighed 365 pounds, stood 38 inches tall at the
shoulder and measured 8 feet, 5 inches in length - that's big...

John Caldecott.

Beagle: Click here.

Basset: Click here.

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